INTRODUCING MODULIFE, AN INNOVATIVE DIETARY MANAGEMENT SOLUTION FOR CROHN’S DISEASE
THIS CONTENT IS FOR HEALTHCARE PROVIDERS ONLY
THE LINK BETWEEN CROHN’S DISEASE & DIET
A large number of adult patients with Crohn’s disease (CD) have questions related to their diet. Many patients adapt their diet by avoiding certain foods to help in managing their CD1. The question that adult patients with CD most often ask is “Doctor, what should I be eating?”1,2
62% of adult patients believe that diet is important in influencing the disease course.3
59% value nutrition to be equally important or more important to medication.3
1.Kane S. Expert Rev Gastroenterol Hepatol. 2012;6(5):545-7.
2.Zallot C et al. Inflamm Bowel Dis. 2013;19(1):66-72.
3. de Vries JHM et al. Dig Dis. 2018 Nov 2:1-9.
“When a patient feels that they cannot partake in social events or even the same meal in their household, this contributes to a lower quality of life and even depression.”
Evidence demonstrates that diet is implicated in the pathogenesis of CD
Numerous studies show the link between the intake of specific food and the risk of developing CD1.
- Heredity explains only up to 26% of why some children develop CD1,2.
- There is an accepted link between the Westernized diet and the incidence of CD1.
- Diet is acknowledged as an adjunct therapy in the treatment of CD in adults3.
In fact, diet plays a key role in altering1 microbiota, host barrier function, innate immunity, and the metabolome.
There is a need for a complete management strategy to tackle the complexity of CD in adults.
High fat, high sugar, low fiber, animal protein, low resistance starch diets, as well as gluten & additives affect both the host and the microbiome1.
1. Levine A, et al. Gut. 2018;66:1-13.
2. Peters LA et al. Nat Genet 2017;49:1437–49.
3. Lichtenstein GR et al. Am J Gastroenterol. 2018;113(4):481-517.
WHAT IS THE MODULIFE DIET?
The CDED therapy induces remission in early mild-to-moderate luminal CD in adults
The CDED therapy results in high remission rates with a decrease in inflammation.1
- 69% of adult patients achieve remission following a 6 week CDED therapy1.
- 63.6% of adult patients with relapses achieved remission1.
A dietary intervention in mild-to moderate disease, based on 50% PEN and a structured diet that excludes certain food can induce clinical remission with a reduction in inflammatory markers.1
The CDED therapy1:
✓ allows access to specific foods to improve palatability
✓ provides an alternative to steroids and biologics induction of remission in mild-to moderate disease for some patients
✓ helps in maintaining remission
✓ is well tolerated.
1. Sigall-Boneh R et al. Inflamm Bowel Dis. 2014 Aug;20(8):1353-60.
2. Levine A et al., Crohn’s Disease Exclusion Diet Plus Partial Enteral Nutrition Induces Sustained Remission in a Randomized Controlled Trial. Gastroenterology. 2019;157(2):440–450. doi: 10.1053/j.gastro.2019.04.021.
BECOME AN EXPERT
Interested in becoming a ModuLife expert?
Register for a structured medical training designed for healthcare professional learning at www.modulifexpert.com
✓ Learn more about the principles of the CDED and the clinical data in support of this novel dietary approach
✓ Available online in e-learning format
✓ Complete the 3 modules to become a certified ModuLife expert
✓ Once complete, you will have the ability to add patients to the ModuLife patient support platform
THE MODULIFE PLATFORM
The ModuLife patient platform has been designed to support patients through each phase of the CDED. Healthcare providers can also access this platform to stay involved in each patient’s journey and easily monitor progress and compliance, even in between office visits
✓ Track food intake, diet adherence, and well-being
✓ Watch videos and read articles to learn more about the CDED and get practical tips on each phase
✓ Access a large selection of CDED-friendly recipes and meal plans
✓ Message nutrition specialists about the CDED, anywhere, anytime
Benefits of the Platform
• Support patient acceptance, compliance, and daily management of the diet
• Provide patients with diet-related educational resources
• Facilitate more efficient office visits and more effective care
ModulenTM is a Food for Special Medical Purposes to be used under medical supervision. This content is for healthcare professionals only.